Professor Psaltis has been Dean of the School of Engineering at EPFL since 2007. He is one of the founders of the term and the field of optofluidics. He is also well known for his past work in holography, especially with regards to optical computing, holographic data storage, and neural networks.
From 1980 to 2007, Professor Psaltis worked at Caltech as an Assistant Professor (1980–1985), Associate Professor (1985–1990), Full Professor (1990–1996), Executive Officer for Computation and Neural Systems (1992–1996), Director for the National Science Foundation Center for Neuromorphic Systems Engineering (1996–1999), Thomas G. Myers Professor (1996–2007) and Director for the DARPA Center for Optofluidic Integration (2004–2007). He received his B.S. (1974), M.S. (1975), and Ph.D. (1977) at Carnegie Mellon University.